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Stem cells and differentiation Lab Description

Key Elements

Code

BIOA 439

Formation

M1 Cellular and Molecular Biology - Section 2

Semester

2

Credits

2

Number of Teaching Hours

0

Number of Tutoring Sessions

0

Number of Laboratory Sessions

24

This course is optional

Content

Objective

The main objectives of this course focus on the intake of knowledge, fundamental bases, and necessary tools for understanding (1) primary cells that are the source of the stem cells and (2) mechanisms of proliferation and differentiation of these stem cells. A general review of the different types of stem cells, their progentors, final forms, niches, membership and their regulation by their surrounding microenvironment, as well as differentiation will be represented. Therapeutic approaches and their use are important in order to show their ways of utilization in medicine. Application: leukemia, muscular diseases, cancer, brain diseases, neuronal, obesity, cardiovascular disease. Importance of cells in plastic surgery.

Content

Concept of stem cell Transcription factors involved in cell differentiation Embryonic stem cells Adult stem cells Stem cells and ethics Hematopoietic Stem Cells Muscle stem cells Neural stem cells Mesenchymal stem cells Gametes and stem cells Vegetal stem cells References • Stem cells Edited by C S potten, Academic Press • Stem cells from Bench to Bedside: Ariff bongso, Eng hin Lee • The Stem cell divide, Michael Bellomo Cell lineage and fate determination, Sally A Moody, 2000